An estimated 1 million cancer diagnoses have been missed across Europe in the last two years. Experts warn of a ‘cancer epidemic in the next decade.’ A new Lancet Oncology Commission outlines steps to strengthen the research landscape in “European Groundshot—addressing Europe’s cancer research challenges: a Lancet Oncology Commission“. The Commission’s research and recommendations could be “powerful drivers of change if all actors are willing to listen and to put artificial divisions to one side.” Editors of this piece, published November 15, 2022, urge collaboration for the sake of cancer research and outcomes.