Project Publications

COLOSSUS publications will be added here as articles are published.

  1. M. Sturrock, I. S. Miller, G. Kang, N. Hannis Arba’ie, A. C. O’Farrell, A. Barat, G. Marston, P. L. Coletta, A. T. Byrne, J. H. Prehn,  Anti-angiogenic drug scheduling optimisation with application to colorectal cancer, Scientific Reports, Volume 8, Article number: 11182 (2018)DOI: 10.1038/s41598-018-29318-5  Download the pdf here.
  2. Florent Petitprez, Cheng-Ming Sun, Laetitia Lacroix, Catherine Sautès-Fridman, Aurélien de Reyniès and Wolf H. Fridman, Quantitative analyses of the tumor microenvironment composition and orientation in the era of precision medicine, Frontiers in Oncology, September 25, 2018, DOI: 10.3389/fonc.2018.00390. Download the pdf here.
  3. O’Farrell AC, Miller IS, Evans R, Alamanou M, Cary M, Mallya Udupi G, Lafferty A, Monsefi N, Cremona M, Prehn JHM, Verheul HM, Gallagher WM, Gehrmann M, Byrne AT, Implementing Reverse Phase Protein Array Profiling as a Sensitive Method for the Early Pre-Clinical Detection of Off-Target Toxicities Associated with Sunitinib Malate, 2019 Feb 15:e1800159. DOI: 10.1002/prca.201800159. Embargoed until 15 February 2020. Repository link:
  4. Caterina Thomaseth, Dirk Fey, Tapesh Santra, Oleksii S. Rukhlenko, Nicole E. Radde, and Boris N. Kholodenko, Impact of measurement noise, experimental design, and estimation methods on Modular Response Analysis based network reconstruction, Sci Rep. 2018; 8: 16217. Published online 2018 Nov 1. DOI: 10.1038/s41598-018-34353-3  Download the pdf here.
  5. Irene Catalano and Livio Trusolino, The Stromal and Immune Landscape of Colorectal Cancer Progression during Anti-EGFR Therapy, Cancer Cell, Volume 36, Issue 1, 8 July 2019, Pages 1-3, DOI: 10.1016/j.ccell.2019.06.001
  6. Elke Burgermeister, Francesca BattaglinFagr Eladly, Wen Wu, Frank Herweck , Nadine Schulte, Johannes Betge, Nicolai HärtelJakob N. Kather, Cleo-Aron Weis, Timo Gaiser, Alexander Marx, Christel Weiss, Ralf Hofheinz, Ian S. Miller, Fotios Loupakis, Heinz-Josef Lenz, Annette T. Byrne, Matthias P. Ebert, Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A,  2019 Jul;45:139-154. DOI: 10.1016/j.ebiom.2019.07.004. Epub 2019 Jul 9. Download the pdf here.